6  Build 04 · Single-cell RNA-seq System

Published

May 2026

A structured single-cell workflow for cell-level transcriptomic analysis and interpretation.

6.1 System Path

Code
flowchart TD

    A[Raw Counts]
    B[Cell and Gene QC]
    C[Normalization]
    D[Dimensional Reduction]
    E[Clustering]
    F[Marker Detection]
    G[Cell Annotation]
    H[Biological Interpretation]
    I[Reporting]

    A --> B
    B --> C
    C --> D
    D --> E
    E --> F
    F --> G
    G --> H
    H --> I

    style A fill:#dbeafe,stroke:#2563eb,stroke-width:2px,color:#0f172a
    style B fill:#e0f2fe,stroke:#0284c7,stroke-width:2px,color:#0f172a
    style C fill:#ecfeff,stroke:#0891b2,stroke-width:2px,color:#0f172a
    style D fill:#ede9fe,stroke:#7c3aed,stroke-width:2px,color:#0f172a
    style E fill:#f3e8ff,stroke:#9333ea,stroke-width:2px,color:#0f172a
    style F fill:#fae8ff,stroke:#c026d3,stroke-width:2px,color:#0f172a
    style G fill:#fef3c7,stroke:#d97706,stroke-width:2px,color:#0f172a
    style H fill:#ecfccb,stroke:#65a30d,stroke-width:2px,color:#0f172a
    style I fill:#f0fdf4,stroke:#16a34a,stroke-width:2px,color:#0f172a

flowchart TD

    A[Raw Counts]
    B[Cell and Gene QC]
    C[Normalization]
    D[Dimensional Reduction]
    E[Clustering]
    F[Marker Detection]
    G[Cell Annotation]
    H[Biological Interpretation]
    I[Reporting]

    A --> B
    B --> C
    C --> D
    D --> E
    E --> F
    F --> G
    G --> H
    H --> I

    style A fill:#dbeafe,stroke:#2563eb,stroke-width:2px,color:#0f172a
    style B fill:#e0f2fe,stroke:#0284c7,stroke-width:2px,color:#0f172a
    style C fill:#ecfeff,stroke:#0891b2,stroke-width:2px,color:#0f172a
    style D fill:#ede9fe,stroke:#7c3aed,stroke-width:2px,color:#0f172a
    style E fill:#f3e8ff,stroke:#9333ea,stroke-width:2px,color:#0f172a
    style F fill:#fae8ff,stroke:#c026d3,stroke-width:2px,color:#0f172a
    style G fill:#fef3c7,stroke:#d97706,stroke-width:2px,color:#0f172a
    style H fill:#ecfccb,stroke:#65a30d,stroke-width:2px,color:#0f172a
    style I fill:#f0fdf4,stroke:#16a34a,stroke-width:2px,color:#0f172a

6.2 Planned Tools

  • Seurat
  • Scanpy
  • SingleCellExperiment
  • UMAP / PCA
  • Quarto
  • 6.3 Status

Active flagship build.

6.4 Live Build

singlecell.complexdatainsights.com